New Melanoma Treatment Might Delay Cancer Progression
Updated: 2012-09-29 16:06:16
Health News New Melanoma Treatment Might Delay Cancer Progression Print E-mail SATURDAY , Sept . 29 HealthDay News Researchers say they've discovered a two-drug combination that delays treatment resistance in patients with advanced . melanoma By targeting different points in the same growth-factor pathway , the kinase inhibitor drugs dabrafenib and trametinib postponed the development of drug resistance in patients with BRAF-positive metastatic melanoma , the study authors . said Melanoma is the most serious , and often deadly , form of skin cancer . In about half of patients with melanoma that has spread , tumor growth is caused by genetic mutations that keep the BRAF protein part of the MAPK cell growth pathway constantly activated . Drugs that inhibit BRAF activity can rapidly stop and